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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNN4
All Species:
19.09
Human Site:
S388
Identified Species:
42
UniProt:
O15554
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15554
NP_002241.1
427
47696
S388
L
Q
Q
N
L
S
S
S
H
R
A
L
E
K
Q
Chimpanzee
Pan troglodytes
XP_512722
385
43303
S346
L
Q
Q
N
L
S
S
S
H
R
A
L
E
K
Q
Rhesus Macaque
Macaca mulatta
XP_001101360
251
28074
H213
Q
Q
N
L
S
S
S
H
R
A
L
E
K
Q
I
Dog
Lupus familis
XP_541579
427
47648
S388
L
Q
L
G
L
S
S
S
H
Q
A
L
E
K
R
Cat
Felis silvestris
Mouse
Mus musculus
O89109
425
47765
S386
L
Q
L
G
L
S
S
S
H
R
A
L
E
K
R
Rat
Rattus norvegicus
Q9QYW1
425
47748
S386
L
Q
L
G
L
S
A
S
H
L
A
L
E
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521824
487
53009
V360
L
A
V
G
R
E
R
V
C
C
S
H
A
P
S
Chicken
Gallus gallus
NP_990129
553
61999
R473
M
I
S
D
L
N
E
R
S
E
D
F
E
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696782
747
85306
S695
L
S
A
N
W
N
S
S
Y
H
E
L
E
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KVW5
924
101426
R847
I
I
S
D
M
S
S
R
Q
D
A
I
E
E
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11122
471
54319
N433
F
S
E
N
N
S
Q
N
N
P
Q
M
T
R
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
57.6
90.6
N.A.
87.1
85.9
N.A.
51.7
37.2
N.A.
28.9
N.A.
21.6
N.A.
27.8
N.A.
Protein Similarity:
100
89.2
58
93.9
N.A.
91.5
90.8
N.A.
58.9
50.8
N.A.
38.1
N.A.
31.9
N.A.
47.5
N.A.
P-Site Identity:
100
100
20
73.3
N.A.
80
66.6
N.A.
6.6
20
N.A.
40
N.A.
26.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
33.3
86.6
N.A.
86.6
80
N.A.
13.3
46.6
N.A.
66.6
N.A.
66.6
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
10
0
0
10
55
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
0
0
0
0
10
10
0
0
0
0
% D
% Glu:
0
0
10
0
0
10
10
0
0
10
10
10
73
10
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
37
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
46
10
0
10
0
0
0
% H
% Ile:
10
19
0
0
0
0
0
0
0
0
0
10
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
55
0
% K
% Leu:
64
0
28
10
55
0
0
0
0
10
10
55
0
0
10
% L
% Met:
10
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
10
37
10
19
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% P
% Gln:
10
55
19
0
0
0
10
0
10
10
10
0
0
19
19
% Q
% Arg:
0
0
0
0
10
0
10
19
10
28
0
0
0
10
55
% R
% Ser:
0
19
19
0
10
73
64
55
10
0
10
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _